Getahun Darios, Demissie Kitaw, Lu Shou-En, Rhoads George G
Department of Family Medicine, UMDNJ-RWJMS, New Brunswick, NJ, USA.
J Perinatol. 2004 Sep;24(9):544-51. doi: 10.1038/sj.jp.7211140.
To compare the incidence and risk factors for sudden infant death syndrome (SIDS) in twin and singleton births and to estimate the concordance of SIDS in twins.
A cohort analysis using the National Center for Health Statistics Linked Birth and Infant Death files (1995-1998).
Twins had higher SIDS rate (1.3/1000 live births) compared to singletons (0.7/1000 live births), relative risk: 1.9, 95% confidence interval: 1.68, 2.01. Male and small- for-gestational age infants as well as infants of black, unmarried, and smoking mothers were at increased risk for SIDS in both twins and singletons. Placental abnormalities also were associated with SIDS in singletons and twins, although this association failed to achieve statistical significance in twins. There is a higher rate of SIDS in the second twin after a first twin SIDS.
Twins are at higher risk of SIDS than are singletons. Overall, the epidemiology of SIDS in twins is quite similar to that seen in singletons.
比较双胎和单胎出生时婴儿猝死综合征（SIDS）的发病率及危险因素，并评估双胞胎中SIDS的一致性。
采用国家卫生统计中心的出生与婴儿死亡关联档案（1995 - 1998年）进行队列分析。
与单胎（0.7/1000活产）相比，双胎的SIDS发生率更高（1.3/1000活产），相对风险为1.9，95%置信区间为1.68至2.01。双胎和单胎中，男性、小于胎龄儿以及母亲为黑人、未婚和吸烟的婴儿发生SIDS的风险增加。胎盘异常在单胎和双胎中也与SIDS有关，尽管这种关联在双胎中未达到统计学显著性。在第一个双胞胎发生SIDS后，第二个双胞胎发生SIDS的几率更高。
双胎发生SIDS的风险高于单胎。总体而言，双胎中SIDS的流行病学与单胎中所见颇为相似。
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