麻腮风疫苗与自闭症之间的关系。
Relationship between MMR vaccine and autism.
作者信息
Klein Kristin C, Diehl Emily B
机构信息
Clinical Sciences Department, College of Pharmacy Services, University of Michigan Health System, Ann Arbor, MI 48109-0221, USA.
出版信息
Ann Pharmacother. 2004 Jul-Aug;38(7-8):1297-300. doi: 10.1345/aph.1D293. Epub 2004 Jun 1.
OBJECTIVE
To evaluate the proposed link between the administration of the measles, mumps, and rubella (MMR) vaccine and the development of autism.
DATA SOURCES
A literature search utilizing MEDLINE (1966-November 2003), with the key terms measles, mumps, rubella, and autism, was conducted. Review of the references listed in the articles identified was also performed.
DATA SYNTHESIS
Ten articles that specifically evaluated the possible relationship between the MMR vaccine and autism were identified. Review articles, commentaries, and evaluations of a link between gastrointestinal symptoms in autistic children and MMR immunization were excluded.
CONCLUSIONS
Based upon the current literature, it appears that there is no relationship between MMR vaccination and the development of autism.
目的
评估麻疹、腮腺炎和风疹（MMR）疫苗接种与自闭症发展之间的假定联系。
数据来源
利用MEDLINE（1966年至2003年11月）进行文献检索，关键词为麻疹、腮腺炎、风疹和自闭症。还对所识别文章中列出的参考文献进行了审查。
数据综合
确定了十篇专门评估MMR疫苗与自闭症之间可能关系的文章。排除了关于自闭症儿童胃肠道症状与MMR免疫之间联系的综述文章、评论和评估。
结论
基于当前文献，MMR疫苗接种与自闭症发展之间似乎没有关系。
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