Chironna Maria, Lopalco Pierluigi, Prato Rosa, Germinario Cinzia, Barbuti Salvatore, Quarto Michele
Hygiene Section, Department of Internal Medicine and Public Health, University of Bari, Policlinico Piazza G, Cesare 11, 70124 Bari, Italy.
J Clin Microbiol. 2004 Jun;42(6):2825-8. doi: 10.1128/JCM.42.6.2825-2828.2004.
An outbreak of infection with hepatitis A virus associated with a foodhandler and involving 26 subjects occurred in Southern Italy. Sequence analysis of the VP3-VP1 and VP1-P2A junctions confirmed that the outbreak was due to a point source and allowed the identification of a new genotype IB variant. This report confirms the usefulness of sequence-based molecular fingerprinting during outbreaks.
在意大利南部发生了一起与一名食品处理人员相关的甲型肝炎病毒感染暴发,涉及26名受试者。对VP3-VP1和VP1-P2A连接区的序列分析证实,此次暴发是由一个点源引起的,并鉴定出一种新的IB基因型变体。本报告证实了基于序列的分子指纹图谱在疫情暴发期间的实用性。