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230名潜水员减压病风险与卵圆孔未闭的存在及大小的关系

Risk of decompression illness among 230 divers in relation to the presence and size of patent foramen ovale.

作者信息

Torti Sandra Rea, Billinger Michael, Schwerzmann Markus, Vogel Rolf, Zbinden Rainer, Windecker Stephan, Seiler Christian

机构信息

Department of Cardiology, University Hospital, CH-3010 Bern, Switzerland.

出版信息

Eur Heart J. 2004 Jun;25(12):1014-20. doi: 10.1016/j.ehj.2004.04.028.

Abstract

BACKGROUND

The risk of developing decompression illness (DCI) in divers with a patent foramen ovale (PFO) has not been directly determined so far; neither has it been assessed in relation to the PFO's size.

METHODS

In 230 scuba divers (age 39+/-8 years), contrast trans-oesophageal echocardiography (TEE) was performed for the detection and size grading (0-3) of PFO. Prior to TEE, the study individuals answered a detailed questionnaire about their health status and about their diving habits and accidents. For inclusion into the study, > or =200 dives and strict adherence to decompression tables were required.

RESULTS

Sixty-three divers (27%) had a PFO. Overall, the absolute risk of suffering a DCI event was 2.5 per 10(4) dives. There were 18 divers (29%) with, and 10 divers (6%) without, PFO who had experienced > or =1 major DCI events P=0.016. In the group with PFO, the incidence per 10(4) dives of a major DCI, a DCI lasting longer than 24 h and of being treated in a decompression chamber amounted to 5.1 (median 0, interquartile range [IQR] 0-10.0), 1.9 (median 0, IQR 0-4.0) and 3.6 (median 0, IQR 0-9.8), respectively and was 4.8-12.9-fold higher than in the group without PFO (P<0.001). The risk of suffering a major DCI, of a DCI lasting longer than 24 h and of being treated by recompression increased with rising PFO size.

CONCLUSION

The presence of a PFO is related to a low absolute risk of suffering five major DCI events per 10(4) dives, the odds of which is five times as high as in divers without PFO. The risk of suffering a major DCI parallels PFO size.

摘要

背景

迄今为止,尚未直接确定患有卵圆孔未闭(PFO)的潜水员发生减压病(DCI)的风险;也未就PFO的大小对其进行评估。

方法

对230名水肺潜水员(年龄39±8岁)进行经食管对比超声心动图(TEE)检查,以检测PFO并对其大小进行分级(0 - 3级)。在进行TEE检查之前,研究对象需填写一份关于其健康状况、潜水习惯及潜水事故的详细问卷。纳入研究的条件为潜水次数≥200次且严格遵守减压表。

结果

63名潜水员(27%)患有PFO。总体而言,每10⁴次潜水发生DCI事件的绝对风险为2.5例。有18名(29%)患有PFO和10名(6%)未患有PFO的潜水员经历过≥1次严重DCI事件(P = 0.016)。在患有PFO的组中,每10⁴次潜水发生严重DCI、持续时间超过24小时的DCI以及在减压舱接受治疗的发生率分别为5.1(中位数0,四分位间距[IQR] 0 - 10.0)、1.9(中位数0,IQR 0 - 4.0)和3.6(中位数0,IQR 0 - 9.8),分别比未患有PFO的组高4.8 - 12.9倍(P < 0.001)。发生严重DCI、持续时间超过24小时的DCI以及接受再加压治疗的风险随PFO大小的增加而升高。

结论

PFO的存在与每10⁴次潜水发生5例严重DCI事件的低绝对风险相关,其发生几率是未患有PFO的潜水员的5倍。发生严重DCI的风险与PFO大小平行。

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