Torti Sandra Rea, Billinger Michael, Schwerzmann Markus, Vogel Rolf, Zbinden Rainer, Windecker Stephan, Seiler Christian
Department of Cardiology, University Hospital, CH-3010 Bern, Switzerland.
Eur Heart J. 2004 Jun;25(12):1014-20. doi: 10.1016/j.ehj.2004.04.028.
The risk of developing decompression illness (DCI) in divers with a patent foramen ovale (PFO) has not been directly determined so far; neither has it been assessed in relation to the PFO's size.
In 230 scuba divers (age 39+/-8 years), contrast trans-oesophageal echocardiography (TEE) was performed for the detection and size grading (0-3) of PFO. Prior to TEE, the study individuals answered a detailed questionnaire about their health status and about their diving habits and accidents. For inclusion into the study, > or =200 dives and strict adherence to decompression tables were required.
Sixty-three divers (27%) had a PFO. Overall, the absolute risk of suffering a DCI event was 2.5 per 10(4) dives. There were 18 divers (29%) with, and 10 divers (6%) without, PFO who had experienced > or =1 major DCI events P=0.016. In the group with PFO, the incidence per 10(4) dives of a major DCI, a DCI lasting longer than 24 h and of being treated in a decompression chamber amounted to 5.1 (median 0, interquartile range [IQR] 0-10.0), 1.9 (median 0, IQR 0-4.0) and 3.6 (median 0, IQR 0-9.8), respectively and was 4.8-12.9-fold higher than in the group without PFO (P<0.001). The risk of suffering a major DCI, of a DCI lasting longer than 24 h and of being treated by recompression increased with rising PFO size.
The presence of a PFO is related to a low absolute risk of suffering five major DCI events per 10(4) dives, the odds of which is five times as high as in divers without PFO. The risk of suffering a major DCI parallels PFO size.
迄今为止,尚未直接确定患有卵圆孔未闭(PFO)的潜水员发生减压病(DCI)的风险;也未就PFO的大小对其进行评估。
对230名水肺潜水员(年龄39±8岁)进行经食管对比超声心动图(TEE)检查,以检测PFO并对其大小进行分级(0 - 3级)。在进行TEE检查之前,研究对象需填写一份关于其健康状况、潜水习惯及潜水事故的详细问卷。纳入研究的条件为潜水次数≥200次且严格遵守减压表。
63名潜水员(27%)患有PFO。总体而言,每10⁴次潜水发生DCI事件的绝对风险为2.5例。有18名(29%)患有PFO和10名(6%)未患有PFO的潜水员经历过≥1次严重DCI事件(P = 0.016)。在患有PFO的组中,每10⁴次潜水发生严重DCI、持续时间超过24小时的DCI以及在减压舱接受治疗的发生率分别为5.1(中位数0,四分位间距[IQR] 0 - 10.0)、1.9(中位数0,IQR 0 - 4.0)和3.6(中位数0,IQR 0 - 9.8),分别比未患有PFO的组高4.8 - 12.9倍(P < 0.001)。发生严重DCI、持续时间超过24小时的DCI以及接受再加压治疗的风险随PFO大小的增加而升高。
PFO的存在与每10⁴次潜水发生5例严重DCI事件的低绝对风险相关,其发生几率是未患有PFO的潜水员的5倍。发生严重DCI的风险与PFO大小平行。