Chen Yee-Chun, Huang Li-Min, Chan Chang-Chuan, Su Chan-Ping, Chang Shan-Chwen, Chang Ying-Ying, Chen Mei-Ling, Hung Chien-Ching, Chen Wen-Jone, Lin Fang-Yue, Lee Yuan-Teh
Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.
Emerg Infect Dis. 2004 May;10(5):782-8. doi: 10.3201/eid1005.030579.
Thirty-one cases of severe acute respiratory syndrome (SARS) occurred after exposure in the emergency room at the National Taiwan University Hospital. The index patient was linked to an outbreak at a nearby municipal hospital. Three clusters were identified over a 3-week period. The first cluster (5 patients) and the second cluster (14 patients) occurred among patients, family members, and nursing aids. The third cluster (12 patients) occurred exclusively among healthcare workers. Six healthcare workers had close contact with SARS patients. Six others, with different working patterns, indicated that they did not have contact with a SARS patient. Environmental surveys found 9 of 119 samples of inanimate objects to be positive for SARS coronavirus RNA. These observations indicate that although transmission by direct contact with known SARS patients was responsible for most cases, environmental contamination with the SARS coronavirus may have lead to infection among healthcare workers without documented contact with known hospitalized SARS patients.
台湾大学医院急诊室在出现暴露情况后，有31例严重急性呼吸综合征（SARS）病例发生。首例患者与附近一家市立医院的疫情爆发有关。在3周内确定了3个聚集性病例组。第一组（5例患者）和第二组（14例患者）出现在患者、家属和护理人员中。第三组（12例患者）仅出现在医护人员中。6名医护人员与SARS患者有密切接触。另外6名医护人员工作模式不同，表明他们未接触过SARS患者。环境调查发现，119份无生命物体样本中有9份SARS冠状病毒RNA呈阳性。这些观察结果表明，尽管大多数病例是通过与已知SARS患者直接接触传播的，但SARS冠状病毒造成的环境污染可能导致了未记录有与已知住院SARS患者接触史的医护人员感染。
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