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膝关节检查的磁共振成像:临床与经济评估

Magnetic resonance imaging for investigation of the knee joint: a clinical and economic evaluation.

作者信息

Bryan Stirling, Bungay Hilary P, Weatherburn Gwyn, Field Stuart

机构信息

Health Economics Facility, University of Birmingham, Brunel University, Birmingham, UK.

出版信息

Int J Technol Assess Health Care. 2004 Spring;20(2):222-9. doi: 10.1017/s026646230400100x.

Abstract

OBJECTIVES

The aim of the study reported here was to investigate whether the use of magnetic resonance imaging (MRI) impacts on the clinical management of patients presenting with chronic knee problems, reduces costs, and improves patient outcome.

METHODS

A single-center randomized controlled trial was conducted. Patients attending with knee problems in whom surgery was being considered were randomized either to investigation using an MRI scan or to investigation using arthroscopy. The study investigated benefits in terms of avoidance of surgery and patient health-related quality of life (using SF-36 and EQ-5D). Costs were assessed from the perspectives of the National Health Service and patients. All analyses were by intention to treat.

RESULTS

The trial recruited 118 patients. No statistically significant differences were found between groups in terms of health outcome. However, the use of MRI was associated with a positive diagnostic/therapeutic impact: a significantly smaller proportion of patients in the MRI group underwent surgery (MRI = 0.41, No-MRI = 0.71; p value = .001). There was a similar mean overall cost for both groups.

CONCLUSIONS

The use of MRI in patients with chronic knee problems, in whom surgery was being considered, did not increase costs overall, was not associated with worse outcomes, and avoided surgery in a significant proportion of patients.

摘要

目的

本研究旨在调查使用磁共振成像(MRI)是否会影响慢性膝关节问题患者的临床管理、降低成本并改善患者预后。

方法

开展了一项单中心随机对照试验。因膝关节问题前来就诊且考虑进行手术的患者被随机分为两组,一组接受MRI扫描检查,另一组接受关节镜检查。该研究从避免手术和患者健康相关生活质量(使用SF - 36和EQ - 5D)方面调查了获益情况。从英国国家医疗服务体系和患者的角度评估了成本。所有分析均采用意向性分析。

结果

该试验招募了118名患者。两组在健康结局方面未发现统计学上的显著差异。然而,MRI的使用具有积极的诊断/治疗影响:MRI组接受手术的患者比例显著更低(MRI组 = 0.41,非MRI组 = 0.71;p值 = 0.001)。两组的平均总成本相似。

结论

对于考虑进行手术的慢性膝关节问题患者,使用MRI总体上不会增加成本,与更差的结局无关,并且在相当比例的患者中避免了手术。

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