Meylaerts S A, van Gulik T M, Rauws E A, Gouma D J
Afd. Chirurgie, Academisch Medisch Centrum/Universiteit van Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam.
Ned Tijdschr Geneeskd. 2004 Jun 5;148(23):1157-61.
Obstructive jaundice occurred in 3 patients, 2 women, aged 44 and 60 years, and one man aged 62 years: 17 years after choledochojejunostomy following a complicated cholecystectomy, 8 years after hepatojejunostomy following choledochal cyst removal, and 1 year after laparoscopic cholecystectomy. Percutaneous or endoscopic stent placement was performed in all patients to relieve biliary obstruction. However, stent dysfunction repeatedly resulted in re-stenting of the obstruction. Imaging techniques, as well as endoscopic brush pathology could not distinguish between a benign or malignant stenosis. Explorative laparotomy showed a new growth in all 3 patients, of which 2 were malignant. When obstructive jaundice occurs after surgery of the biliary tract for benign disease, the most likely cause is a benign stenosis. Percutaneous or endoscopic stenting is the treatment of choice. In case of unexpected and/or repeated stent failure, when a diagnosis cannot be made due to inconclusive imaging or pathology of the stenosis exploratory surgery should be considered, as malignant stenosis may be present.
3例患者发生了梗阻性黄疸,其中2例为女性,年龄分别为44岁和60岁,1例为男性,62岁:1例在复杂胆囊切除术后行胆总管空肠吻合术17年后发生;1例在胆总管囊肿切除术后行肝空肠吻合术8年后发生;1例在腹腔镜胆囊切除术后1年发生。所有患者均行经皮或内镜下支架置入术以缓解胆道梗阻。然而,支架功能障碍反复导致梗阻部位再次置入支架。影像学检查以及内镜刷检病理均无法区分良性或恶性狭窄。剖腹探查显示所有3例患者均有新生物,其中2例为恶性。当良性疾病胆道手术后发生梗阻性黄疸时,最可能的原因是良性狭窄。经皮或内镜下支架置入术是首选治疗方法。如果出现意外和/或反复的支架失败,由于狭窄的影像学或病理学检查结果不明确而无法做出诊断时,应考虑进行探查性手术,因为可能存在恶性狭窄。