de la Fouchardière Arnaud, Frachon Sophie, Gengler Carole, Devouassoux-Shisheboran Mojgan
Service d'Anatomie Pathologique, Hôpital de la Croix Rousse, 103 Grande rue de la Croix Rousse, 69317 Lyon 04.
Ann Pathol. 2004 Apr;24(2):172-5. doi: 10.1016/s0242-6498(04)93941-7.
Simultaneous carcinomas involving both the ovary and the endometrium may cause diagnostic difficulties, particularly if the tumors have a similar histology. We report two cases of independent endometrioid carcinomas of the endometrium and the ovary. Tumor development was synchronous in one case and metachronous in the other. These cases illustrate the morphological criteria helpful in distinguishing independent primaries from metastatic carcinomas which have a different therapeutic implication. Endometrial tumors were intra-mucosal without myometrial or vascular invasion, or tubal involvement and were associated with atypical complex hyperplasia (case 2). The ovarian tumors were uninodular, unilateral, without hilar invasion and were associated with endometriosis (case 2). The prognosis of endometrioid type carcinomas is better than for other histological types of carcinoma. Both our patients are well and disease free at 27 and 24 months.
同时累及卵巢和子宫内膜的癌可能会造成诊断困难,尤其是当肿瘤具有相似的组织学特征时。我们报告两例子宫内膜和卵巢独立的子宫内膜样癌病例。其中一例肿瘤发展为同步性,另一例为异时性。这些病例说明了有助于区分独立原发性肿瘤与转移性癌的形态学标准,这两者具有不同的治疗意义。子宫内膜肿瘤位于黏膜内,无肌层或血管侵犯,也无输卵管受累,并伴有非典型复杂性增生(病例2)。卵巢肿瘤为单结节、单侧性,无肺门侵犯,并伴有子宫内膜异位症(病例2)。子宫内膜样癌的预后优于其他组织学类型的癌。我们的两名患者在27个月和24个月时情况良好,无疾病复发。