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蚊子抗杀虫剂的分子基础。

The molecular basis of insecticide resistance in mosquitoes.

作者信息

Hemingway Janet, Hawkes Nicola J, McCarroll Lynn, Ranson Hilary

机构信息

Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.

出版信息

Insect Biochem Mol Biol. 2004 Jul;34(7):653-65. doi: 10.1016/j.ibmb.2004.03.018.

Abstract

Insecticide resistance is an inherited characteristic involving changes in one or more insect gene. The molecular basis of these changes are only now being fully determined, aided by the availability of the Drosophila melanogaster and Anopheles gambiae genome sequences. This paper reviews what is currently known about insecticide resistance conferred by metabolic or target site changes in mosquitoes.

摘要

杀虫剂抗性是一种涉及一个或多个昆虫基因变化的遗传特性。借助黑腹果蝇和冈比亚按蚊的基因组序列,这些变化的分子基础才刚刚得以全面确定。本文综述了目前已知的由蚊子代谢或靶位点变化所导致的杀虫剂抗性情况。

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