Durrani O M, Meads C A, Murray P I
Academic Unit of Ophthalmology, The University of Birmingham, Birmingham, UK.
Ophthalmologica. 2004 Jul-Aug;218(4):223-36. doi: 10.1159/000078612.
Uveitis (intraocular inflammation) is a potentially blinding group of, probably autoimmune, conditions predominantly occurring in the working age group. Although the aetiology is unknown in most cases, many patients have an associated underlying systemic disease. Central vision loss, in the form of cystoid macular oedema, is the commonest type of visual impairment. Although historical incidence and prevalence data exists, little is known about the degree of vision loss experienced, and the social and financial consequences of having temporary or permanent visual impairment in this age group. The literature is also full of uncontrolled studies and case reports of different modalities of drug therapy for uveitis. This article attempts to raise the awareness of uveitis as an important sight-threatening group of conditions by highlighting the paucity of evidence-based data on epidemiological, quality of life, socioeconomic, and therapeutic aspects.
葡萄膜炎(眼内炎症)是一组可能具有自身免疫性、主要发生在工作年龄组的潜在致盲病症。尽管大多数情况下病因不明,但许多患者伴有潜在的全身性疾病。以黄斑囊样水肿形式出现的中心视力丧失是最常见的视力损害类型。虽然有既往发病率和患病率数据,但对于该年龄组经历的视力丧失程度以及暂时或永久性视力损害的社会和经济后果知之甚少。文献中也充斥着关于葡萄膜炎不同药物治疗方式的非对照研究和病例报告。本文试图通过强调在流行病学、生活质量、社会经济和治疗方面缺乏循证数据,提高人们对葡萄膜炎作为一组重要的视力威胁性病症的认识。