高钙血症性低钙尿症：甲状旁腺功能亢进的关键鉴别诊断。

Hypercalcemic hypocalciuria: a critical differential diagnosis for hyperparathyroidism.

作者信息

Schwartz Seth R, Futran Neal D

机构信息

Department of Otolaryngology Head and Neck Surgery, University of Washington Medical Center, 1959 Northeast Pacific Avenue, Seattle, WA 98195, USA.

出版信息

Otolaryngol Clin North Am. 2004 Aug;37(4):887-96, xi. doi: 10.1016/j.otc.2004.02.015.

DOI:10.1016/j.otc.2004.02.015

PMID:15262523

Abstract

A differential diagnosis for hyperparathyroidism includes all causes of hypercalcemia; the primary causes of which are primary hyperparathyroidism and humoral hypercalcemia of malignancy. Benign familial hypocalciuric hypercalcemia is a rare condition of primary importance because failure to recognize this entity leads to unnecessary surgery. There are a plethora of other rare causes of hypercalcemia that can be distinguished from primary hyperparathyroidism by history and laboratory profiles. This article discusses the main and less common causes of hypercalcemia and provides guidance for distinguishing among them.

摘要

甲状旁腺功能亢进的鉴别诊断包括所有导致高钙血症的病因；其中主要病因是原发性甲状旁腺功能亢进和恶性肿瘤所致的体液性高钙血症。良性家族性低钙血症性高钙血症是一种罕见但至关重要的疾病，因为未能识别该疾病会导致不必要的手术。还有许多其他罕见的高钙血症病因，可通过病史和实验室检查结果与原发性甲状旁腺功能亢进相鉴别。本文讨论了高钙血症的主要和较不常见的病因，并提供了鉴别这些病因的指导。