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18个欧洲国家的宫颈癌筛查项目与政策

Cervical cancer screening programmes and policies in 18 European countries.

作者信息

Anttila A, Ronco G, Clifford G, Bray F, Hakama M, Arbyn M, Weiderpass E

机构信息

The Finnish Cancer Registry, Helsinki, Finland.

出版信息

Br J Cancer. 2004 Aug 31;91(5):935-41. doi: 10.1038/sj.bjc.6602069.

Abstract

A questionnaire survey was conducted by the Epidemiology Working Group of the European Cervical Cancer Screening Network, and the International Agency for Research on Cancer, IARC, between August and December 2003 in 35 centres in 20 European countries with reliable cervical cancer incidence and/or mortality data in databanks held at IARC and WHO. The questionnaire was completed by 28 centres from 20 countries. The final tables included information on 25 centres from 18 countries. Six countries had started screening in the 1960s, whereas 10 countries or regions had started at least a pilot programme by 2003. There were six invitational and nine partially invitational programmes, the rest employing opportunistic screening only. Recommended lifetime number of smears varied from seven to more than 50. Coverage of smear test within the recommended screening interval (usually 3 or 5 years) was above 80% in three countries. Screening registration took place in 13 programmes. Eight programmes reported the rates of screen-detected cervical cancers and precursor lesions. There was wide variation in the CIN3 detection rates. International guidelines and quality assurance protocols are useful for monitoring and evaluating screening programmes systematically. Our survey indicated that the recommendations as currently given are met in only few European countries. Health authorities need to consider stronger measures and incentives than those laid out in the current set of recommendations.

摘要

欧洲宫颈癌筛查网络的流行病学工作组与国际癌症研究机构(IARC)于2003年8月至12月期间,在20个欧洲国家的35个中心开展了一项问卷调查,这些中心在IARC和世界卫生组织(WHO)的数据库中拥有可靠的宫颈癌发病率和/或死亡率数据。来自20个国家的28个中心完成了问卷。最终表格包含了来自18个国家的25个中心的信息。6个国家在20世纪60年代就开始了筛查,而到2003年,有10个国家或地区至少启动了一项试点项目。有6个邀请式项目和9个部分邀请式项目,其余项目仅采用机会性筛查。推荐的终生涂片检查次数从7次到50多次不等。在三个国家,推荐筛查间隔(通常为3年或5年)内的涂片检查覆盖率超过80%。13个项目进行了筛查登记。8个项目报告了筛查发现的宫颈癌和癌前病变的发生率。CIN3(宫颈上皮内瘤变3级)的检出率差异很大。国际指南和质量保证方案有助于系统地监测和评估筛查项目。我们的调查表明,目前给出的建议仅在少数欧洲国家得到了落实。卫生当局需要考虑采取比当前这套建议中规定的更有力的措施和激励措施。

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