膨体聚四氟乙烯移植物愈合过程中纤维长度与组织长入的关系。
Relationship between fibril length and tissue ingrowth in the healing of expanded polytetrafluoroethylene grafts.
作者信息
Hazama Kazuaki, Miura Hidehiko, Shimada Toshifumi, Okuda Yasuhiro, Murashita Toshifumi, Nishibe Toshiya
机构信息
Department of Surgery, Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
出版信息
Surg Today. 2004;34(8):685-9. doi: 10.1007/s00595-004-2774-9.
PURPOSE
To determine whether fibril length is correlated with graft healing as well as cellular and capillary ingrowth in a canine carotid implantation model.
METHODS
Expanded polytetrafluoroethylene (ePTFE) vascular grafts with three different fibril lengths (30, 60, and 90 microm) were implanted into the carotid artery in dogs. They were retrieved 4 weeks later, and subjected to histomorphometric analysis.
RESULTS
Endothelial healing was best in the 60-microm grafts. Not only cellular ingrowth but also capillary ingrowth was most evident in the 60-microm grafts, followed by the 90-microm grafts and then the 30-microm grafts.
CONCLUSION
Better endothelial healing of ePTFE vascular grafts is correlated with more cellular and capillary ingrowth, but more cellular and capillary ingrowth is not correlated with longer fibril length or higher air porosity.
目的
在犬颈动脉植入模型中确定纤维长度是否与移植物愈合以及细胞和毛细血管长入相关。
方法
将具有三种不同纤维长度（30、60和90微米）的膨体聚四氟乙烯（ePTFE）血管移植物植入犬的颈动脉。4周后取出移植物，并进行组织形态计量学分析。
结果
60微米的移植物内皮愈合最佳。细胞长入和毛细血管长入在60微米的移植物中最为明显，其次是90微米的移植物，然后是30微米的移植物。
结论
ePTFE血管移植物更好的内皮愈合与更多的细胞和毛细血管长入相关，但更多的细胞和毛细血管长入与更长的纤维长度或更高的气孔率无关。
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