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减肥手术后继发的营养缺乏症。

Nutrient deficiencies secondary to bariatric surgery.

作者信息

Alvarez-Leite Jacqueline I

机构信息

Biochemistry and Immunology Department, Institute of Biological Sciences and Alfa Institute of Gastroenterology, Clinics Hospital, Medical School, Federal University of Minas Gerais, Brazil.

出版信息

Curr Opin Clin Nutr Metab Care. 2004 Sep;7(5):569-75. doi: 10.1097/00075197-200409000-00010.

Abstract

PURPOSE OF REVIEW

The number of adolescent and adult patients submitting to bariatric surgery is increasing rapidly around the world. This review describes the literature published in the last few years concerning nutritional deficiencies after bariatric surgery as well as their etiology, incidence, treatment and prevention.

RECENT FINDINGS

Although bariatric surgery was first introduced in the 1950s, safe and successful surgical management has progressed over the last two decades and longer post-surgical follow-up data are now available. Most of the patients undergoing malabsorptive procedures will develop some nutritional deficiency, justifying mineral and multivitamin supplementation to all postoperatively. Nutrient deficiency is proportional to the length of absorptive area and to the percentage of weight loss. Low levels of iron, vitamin B12, vitamin D and calcium are predominant after Roux-en-Y gastric bypass. Protein and fat-soluble vitamin deficiencies are mainly detected after biliopancreatic diversion. Thiamine deficiency is common in patients with frequent vomiting. As the incidence of these deficiencies progresses with time, the patients should be monitored frequently and regularly to prevent malnutrition.

SUMMARY

Nutritional deficiencies can be prevented if a multidisciplinary team regularly assists the patient. Malnutrition is generally reverted with nutrient supplementation, once it is promptly diagnosed. Especial attention should be given to adolescents, mainly girls at reproductive age who have a substantial risk of developing iron deficiency. Future studies are necessary to detect nutrient abnormalities after new procedures and to evaluate the safety of bariatric surgery in younger obese patients.

摘要

综述目的

在全球范围内,接受减肥手术的青少年和成年患者数量正在迅速增加。本综述描述了过去几年发表的有关减肥手术后营养缺乏及其病因、发病率、治疗和预防的文献。

最新发现

尽管减肥手术在20世纪50年代首次引入,但在过去二十年中,安全且成功的手术管理取得了进展,现在有了更长时间的术后随访数据。大多数接受吸收不良手术的患者会出现一些营养缺乏,这证明术后对所有患者补充矿物质和多种维生素是合理的。营养缺乏与吸收面积的长度和体重减轻的百分比成正比。在Roux-en-Y胃旁路术后,铁、维生素B12、维生素D和钙水平较低最为常见。蛋白质和脂溶性维生素缺乏主要在胆胰分流术后被检测到。硫胺素缺乏在频繁呕吐的患者中很常见。随着这些缺乏症的发病率随时间推移而上升,应定期对患者进行频繁监测以预防营养不良。

总结

如果一个多学科团队定期协助患者,营养缺乏是可以预防的。一旦及时诊断出营养不良,通常通过补充营养来纠正。应特别关注青少年,主要是处于生育年龄的女孩,她们有患缺铁性贫血的重大风险。未来有必要进行研究,以检测新手术后的营养异常情况,并评估减肥手术在年轻肥胖患者中的安全性。

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