Leis-Márquez M T, Guzmán-Huerta E
Departamento de Medicina Fetal, Instituto Nacional de Perinatología Montes Urales 800, CP 11000 México, DF.
Ginecol Obstet Mex. 1999 Mar;67:113-28.
A review is made of the main prenatal growth stages and the way they are influenced by social and biological factors pointing out the role of maternal nutrition before and during pregnancy. It is discussed the available evidence on the relation of maternal nutrition and fetal growth through clinical and epidemiological studies performed in animal and humans, analyzing the causal mechanisms of this association, including the role of placenta. Some clinical useful indicators that allow to evaluate maternal nutrition throughout gestation are presented. Emphasis is made on the impact of protein-energy malnutrition as well as on some specific deficiencies, particularly iron and folic acid. At last, the synergic effect of infection and malnutrition on low birth weight and prematurity is analyzed.
本文综述了主要的产前生长阶段以及它们受社会和生物因素影响的方式,指出了孕期前后母体营养的作用。通过在动物和人类身上进行的临床和流行病学研究,讨论了关于母体营养与胎儿生长关系的现有证据,分析了这种关联的因果机制,包括胎盘的作用。介绍了一些有助于评估整个孕期母体营养状况的临床有用指标。重点强调了蛋白质 - 能量营养不良的影响以及一些特定营养素缺乏的影响,特别是铁和叶酸。最后,分析了感染和营养不良对低出生体重和早产的协同作用。