Chau Ian, Legge Sally, Fumoleau Pierre
Department of Medicine, Royal Marsden Hospital, Fulham Road, London and Surrey, SW3 6JJ, UK.
Eur J Oncol Nurs. 2004;8 Suppl 1:S41-53. doi: 10.1016/j.ejon.2004.06.008.
Use of oral capecitabine (Xeloda) as home-based therapy leads to savings in healthcare resources and costs and oral chemotherapy is preferred by many cancer patients over intravenous (i.v.) 5-FU. The demands of patient management for oral therapy differ significantly from those of i.v. chemotherapy. Consequently, cancer programmes have begun to implement strategies to meet these unique demands, offer educational programmes for clinicians who prescribe capecitabine, and consider potential changes in staff responsibilities. To encourage patients to take an active part in their care, which is vital with home-based oral therapy, they must be properly informed about their treatment. Patient information needs to be specific for the cancer type and relevant for the country. Various tools have been developed, including prescription guides, diary cards and support kits, which are useful in reinforcing verbal discussions about the use of capecitabine and in helping patients to manage their treatment. Nurses have a vital role to play in encouraging the optimal use of capecitabine and prompt management of adverse events, thereby enabling the patient to achieve a better clinical outcome and maintain an improved quality of life in the home environment.
使用口服卡培他滨(希罗达)作为居家治疗可节省医疗资源和成本,并且比起静脉注射5-氟尿嘧啶,许多癌症患者更倾向于口服化疗。口服治疗的患者管理需求与静脉化疗的需求显著不同。因此,癌症治疗项目已开始实施策略以满足这些独特需求,为开卡培他滨处方的临床医生提供教育项目,并考虑员工职责的潜在变化。为鼓励患者积极参与自身护理(这对居家口服治疗至关重要),必须让他们充分了解自己的治疗情况。患者信息需要针对癌症类型且与所在国家相关。已开发出各种工具,包括处方指南、日记卡和支持包,这些工具有助于加强关于卡培他滨使用的口头讨论,并帮助患者管理自己的治疗。护士在鼓励优化使用卡培他滨以及及时处理不良事件方面起着至关重要的作用,从而使患者能够取得更好的临床结果,并在居家环境中维持改善后的生活质量。