Lee Seung-Ju, Kim Sae Woong, Cho Yong-Hyun, Shin Wan-Shik, Lee Sang Eun, Kim Choung-Soo, Hong Sung Joon, Chung Byung Ha, Kim Jung Ju, Yoon Moon Soo
Department of Urology, St. Mary's Hospital, Catholic University, 62 Yeouido-dong, Yeongdeungpo-gu, Seoul 150-713, South Korea.
Int J Antimicrob Agents. 2004 Sep;24 Suppl 1:S65-9. doi: 10.1016/j.ijantimicag.2004.02.013.
The efficacy of nitrofurazone-coated urinary catheter in inhibitory activity of catheter-associated urinary tract infection (CAUTI) was evaluated. The incidence rate and onset of CAUTI after catheterisation of standard silicone urinary catheters and nitrofurazone-coated catheters was compared. There was no statistical significance between the two groups in the incidence rate of CAUTI. However, in patients who had indwelling urinary catheters for 5-7 days, the incidence rate of CAUTI was significantly lower in the experimental group. Logistic regression analysis showed that the two variables, including age and period of insertion, affected the incidence rate of CAUTI significantly. Nitrofurazone-coated catheters can be useful for inhibition of CAUTI in patients who have indwelling urinary catheter for 5-7 days and in old-age patients.
评估了呋喃西林涂层导尿管对导管相关性尿路感染(CAUTI)的抑制活性疗效。比较了标准硅胶导尿管和呋喃西林涂层导尿管插管后CAUTI的发生率和发病情况。两组CAUTI发生率之间无统计学意义。然而,在留置导尿管5 - 7天的患者中,实验组CAUTI发生率显著较低。逻辑回归分析表明,年龄和插管时间这两个变量对CAUTI发生率有显著影响。呋喃西林涂层导尿管可用于抑制留置导尿管5 - 7天的患者及老年患者的CAUTI。