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[局限性或局部晚期前列腺癌的内分泌治疗]

[Endocrine therapy for localized or locally advanced prostate cancer].

作者信息

Fontaine Eric, Ruffion Alain, Staerman Frédéric

机构信息

Service d'Urologie, Hopital Ambroise Paré, Boulogne, France.

出版信息

Prog Urol. 2004 Jun;14(3):433-6.

Abstract

The place of endocrine therapy, either alone or in combination with radiotherapy and surgery, remains highly controversial in the treatment of non-metastatic prostate cancer. The authors review the results of isolated endocrine therapy or associated with local therapy. At the present time, there are few arguments in favour of the use of endocrine therapy in the following situations: isolated treatment of localized or locally advanced cancer prior to radical prostatectomy, after radical prostatectomy. Current data suggest a benefit of endocrine therapy in combination with radiotherapy in patients with high-grade localized or locally advanced cancer.

摘要

在内分泌治疗单独或与放疗及手术联合用于非转移性前列腺癌治疗方面,其地位仍极具争议。作者回顾了单纯内分泌治疗或与局部治疗联合的结果。目前,几乎没有证据支持在以下情况使用内分泌治疗:在根治性前列腺切除术之前对局限性或局部晚期癌进行单独治疗、在根治性前列腺切除术后进行单独治疗。目前的数据表明,对于高级别局限性或局部晚期癌患者,内分泌治疗与放疗联合使用有益。

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