Ozisik Handan Isin, Ersoy Yasemin, Refik Tevfik Mehmet, Kizkin Sibel, Ozcan Cemal
Research Hospital, Turgut Ozal Medical Center, Inonu University Medical Faculty, TR-44330 Malatya, Turkey.
Microbes Infect. 2004 Jul;6(9):861-3. doi: 10.1016/j.micinf.2004.04.012.
Brucella melitensis infection is endemic in the eastern and south-eastern Anatolia regions of Turkey. We report an unusual case of brucella meningitis presenting with bilateral papilla stasis, diplopia and absence of other neurological involvement. Diagnosis was made by positive culture of Brucella spp. with a BACTEC 9120 system with inoculation of the patient's cerebrospinal fluid (CSF). This is the first report of isolation of Brucella spp. from CSF on a BACTEC 9120 system for diagnosis of meningitis. This case demonstrated that brucella meningitis may present with very slight symptoms, and inoculation of CSF into BACTEC bottle besides conventional cultures improves the detection of Brucella in endemic areas such as Turkey.
马尔他布鲁氏菌感染在土耳其安纳托利亚东部和东南部地区呈地方性流行。我们报告了一例罕见的布鲁氏菌脑膜炎病例,表现为双侧视乳头淤血、复视且无其他神经系统受累症状。通过使用BACTEC 9120系统对患者脑脊液(CSF)进行接种培养,布鲁氏菌属呈阳性,从而确诊。这是首例在BACTEC 9120系统上从脑脊液中分离出布鲁氏菌属用于脑膜炎诊断的报告。该病例表明,布鲁氏菌脑膜炎可能仅表现出非常轻微的症状,并且在土耳其等流行地区,除了传统培养方法外,将脑脊液接种到BACTEC瓶中可提高布鲁氏菌的检测率。