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对幼年雌性野猪进行经典猪瘟口服疫苗接种后母源抗体的产生情况。

Development of maternal antibodies after oral vaccination of young female wild boar against classical swine fever.

作者信息

Kaden Volker, Lange Elke

机构信息

Federal Research Centre for Virus Diseases of Animals, Friedrich-Loeffler-Institutes, Institute of Infectology, Boddenblick 5a, D-17493 Greifswald--Insel Riems, Germany.

出版信息

Vet Microbiol. 2004 Oct 5;103(1-2):115-9. doi: 10.1016/j.vetmic.2004.07.002.

Abstract

An experimental study was performed to investigate the development of maternal antibodies after oral immunisation of young female wild boar against classical swine fever (CSF) using C-strain vaccine. Our results demonstrated that maternal antibodies do not persist in the offspring for more than 3 months. Based on the neutralising serum antibody titres, we assume that piglets of wild sows vaccinated orally twice or immunised once a long time before conception have protective antibodies for approximately 2 months. Furthermore, it seems that the level and the duration of maternal antibodies in the offspring are depend on the age of the female animals at the moment of vaccination as demonstrated in our experiment. The recent vaccination procedure consists of three double vaccinations in spring, summer and autumn. Especially vaccinations in summer and autumn could be crucial for transfer of high maternal antibody titres to the offspring.

摘要

进行了一项实验研究,以调查使用C株疫苗对年轻雌性野猪进行口服免疫以预防经典猪瘟(CSF)后母源抗体的产生情况。我们的结果表明,母源抗体在后代中持续不超过3个月。根据中和血清抗体滴度,我们假设口服接种两次或在受孕前很长时间接种一次的野生母猪所产仔猪有大约2个月的保护性抗体。此外,如我们的实验所示,后代中母源抗体的水平和持续时间似乎取决于接种疫苗时雌性动物的年龄。目前的疫苗接种程序包括在春季、夏季和秋季进行三次双次接种。特别是夏季和秋季的接种对于将高母源抗体滴度传递给后代可能至关重要。

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