Suppr超能文献

[坏死性筋膜炎:我们的经验]

[Necrotizing fasciitis: our experience].

作者信息

Angelici A M, Nasti A G, Montesano G, Simonelli I, Palumbo P

机构信息

Università degli Studi La Sapienza di Roma, Policlinico Umberto I, Dipartimento di Scienze Chirurgiche e Tecnologie Mediche Applicate F. Durante.

出版信息

G Chir. 2004 May;25(5):167-70.

Abstract

Necrotizing fasciitis is a rare and dramatic soft-tissue; infection starting from the subcutaneous tissue, involving the fascia and the underlying muscle and causes necrosis and, suddenly, gangrene. Most frequently the necrotizing fasciitis is localized in anorectal or genitourinary region and in traumatized muscles. Its mortality rate is 20%. Predisposing factors for these infections have included advanced age, obesity, hypertension, atherosclerosis, malnutrition, renal failure, immunosuppression and, primarily, diabetes mellitus. The infection is caused by a lot of gram +, gram -, and anaerobic bacteria that act synergistically. The early diagnosis, a correct chemotherapy, an aggressive surgical treatment of the necrotic area and hyperbaric oxygen treatment allow the patient's recovery, dramatically reducing the functional consequences. The Authors analyze retrospectively five cases of necrotizing fasciitis observed in the last two years (August 2001-August 2003) and stress clinical findings and surgical treatment.

摘要

坏死性筋膜炎是一种罕见且严重的软组织感染,始于皮下组织,累及筋膜及深层肌肉,可导致坏死并迅速发展为坏疽。坏死性筋膜炎最常发生于肛门直肠或泌尿生殖区域以及受创伤的肌肉。其死亡率为20%。这些感染的易感因素包括高龄、肥胖、高血压、动脉粥样硬化、营养不良、肾衰竭、免疫抑制,主要是糖尿病。该感染由多种革兰氏阳性菌、革兰氏阴性菌及厌氧菌协同作用引起。早期诊断、正确的化疗、对坏死区域积极的手术治疗以及高压氧治疗可使患者康复,显著减少功能后果。作者回顾性分析了过去两年(2001年8月至2003年8月)观察到的5例坏死性筋膜炎病例,并强调了临床发现及手术治疗情况。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验