家族性高胆固醇血症：动脉粥样硬化的遗传易感性。

Familial hypercholesterolemia: genetic predisposition to atherosclerosis.

作者信息

Engler Mary B

机构信息

Department of Physiological Nursing, School of Nursing, University of California, San Francisco, CA, USA.

出版信息

Medsurg Nurs. 2004 Aug;13(4):253-7.

PMID:15384479

Abstract

Familial hypercholesterolemia is one of the most frequent genetic disorders. The increased cholesterol levels in the plasma low-density lipoprotein fraction due to the diminished number or absence of LDL receptors predispose affected individuals to premature atherosclerosis and cardiovascular disease.

摘要

家族性高胆固醇血症是最常见的遗传性疾病之一。由于低密度脂蛋白受体数量减少或缺乏，血浆低密度脂蛋白部分中的胆固醇水平升高，使受影响个体易患早发性动脉粥样硬化和心血管疾病。