Markowitz J C, Moran M E, Kocsis J H, Frances A J
Department of Psychiatry, Cornell University Medical College, New York, NY.
J Affect Disord. 1992 Feb;24(2):63-71. doi: 10.1016/0165-0327(92)90020-7.
We investigated prevalence and comorbidity of DSM-III dysthymic disorder in a psychiatric outpatient clinic. Seventy-five consecutive outpatients received structured interviews. Prevalence of dysthymic disorder was 36% in the consecutive sample. Thirty-four dysthymic and 56 non-dysthymic patients were compared for comorbidity. Dysthymic subjects were more likely to meet criteria for major depression, social phobia, and avoidant, self-defeating, dependent, and borderline personality disorders. Dysthymic disorder was usually of early onset, predating comorbid disorders, and had often not received adequate antidepressant treatment. These results help define dysthymic disorder as prevalent, usually predating axis I comorbidity, and associated with particular axis II diagnoses.
我们在一家精神科门诊诊所调查了DSM-III恶劣心境障碍的患病率及共病情况。75名连续就诊的门诊患者接受了结构化访谈。在连续样本中,恶劣心境障碍的患病率为36%。比较了34名恶劣心境障碍患者和56名非恶劣心境障碍患者的共病情况。恶劣心境障碍患者更有可能符合重度抑郁症、社交恐惧症以及回避型、自我挫败型、依赖型和边缘型人格障碍的诊断标准。恶劣心境障碍通常起病较早,早于共病障碍,且往往未得到充分的抗抑郁治疗。这些结果有助于将恶劣心境障碍定义为一种常见疾病,通常早于轴I共病,且与特定的轴II诊断相关。