del Palacio Amalia, Cuétara María Soledad, Pontón José
Servicio de Microbiología, Hospital Universitario Doce de Octubre, Madrid, Spain.
Rev Iberoam Micol. 2003 Sep;20(3):90-8.
Invasive aspergillosis is major cause of morbility and mortality in immunosuppressed patients, in part due to the inability to identify infected patients at an early stage of the disease. Diagnosis is based on a combination of imaging (high-resolution computed tomography) and a number of laboratory techniques including direct examination, culture and circulating markers (galactomannan and Aspergillus DNA) which can be detected at early stages of the infection.
侵袭性曲霉病是免疫抑制患者发病和死亡的主要原因,部分原因是无法在疾病早期识别感染患者。诊断基于影像学检查(高分辨率计算机断层扫描)和多种实验室技术的结合,包括直接检查、培养和循环标志物(半乳甘露聚糖和曲霉DNA),这些标志物可在感染早期检测到。