Kotanidou Anastasia N, Zakynthinos Epaminonthas, Andrianakis Ilias, Zervakis Dimitrios, Kokotsakis Ioannis, Argyrakos Theodoros, Argiropoulou Athina, Margariti Georgia, Douzinas Emmanuel
Department of Critical Care and Pulmonary Services, University of Athens, Athens, Greece.
Ann Thorac Surg. 2004 Oct;78(4):1453-5. doi: 10.1016/j.athoracsur.2003.07.001.
Systemic infection with Aspergillus fumigatus is an opportunistic disease that affects mainly immunocompromised hosts and is associated with a high mortality rate. We report a case of A. fumigatus endocarditis after an episode of thrombotic thrombocytopenic purpura. Diagnosis was established after sudden rupture of posterior papillary muscle of the normal native mitral valve. Soon after mitral valve replacement, Aspergillus endocarditis recurred, associated with multiple peripheral emboli, which necessitated a second operation.
烟曲霉的全身感染是一种机会性疾病,主要影响免疫功能低下的宿主,且死亡率很高。我们报告一例血栓性血小板减少性紫癜发作后发生烟曲霉性心内膜炎的病例。诊断是在正常的天然二尖瓣后乳头肌突然破裂后确定的。二尖瓣置换术后不久,烟曲霉性心内膜炎复发,并伴有多个外周栓子,这使得必须进行第二次手术。