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使用处方药以及补充和替代药物治疗抑郁和焦虑症状:来自社区样本的结果。

Use of prescription medications and complementary and alternative medicines to treat depressive and anxiety symptoms: results from a community sample.

作者信息

Parslow Ruth A, Jorm Anthony F

机构信息

Centre for Mental Health Research, Australian National University, Acton, ACT 0200, Australia.

出版信息

J Affect Disord. 2004 Oct 1;82(1):77-84. doi: 10.1016/j.jad.2003.09.013.

Abstract

BACKGROUND

Individuals prescribed antidepressants or anxiolytics may replace or augment such medications with complementary and alternative medicines (CAMs). Little is known about the extent to which individuals in the community use CAMs instead of, or in addition to, medications they have been prescribed, for anxiety and depressive symptoms.

METHOD

Information on use of CAMs, antidepressants and anxiolytics was obtained from a community sample of 7485 survey participants from Canberra and environs, Australia. Participants aged 20-24, 40-44, or 60-64 were also provided information on sociodemographic attributes, physical and mental health.

RESULTS

6.29% of participants used only prescription medications to treat their depression or anxiety. 2.28% used only CAMs for this purpose while a further 0.59% reported using both types of treatments. Those using CAMs and those who took prescription medications had comparable levels of mental health problems while CAM users had fewer physical health problems and lower neuroticism. Compared with those taking neither CAMs nor prescribed medication, however, CAM users had more depressive and anxiety symptoms, worse mental health, higher neuroticism and lower levels of mastery.

LIMITATIONS

Information on use of prescribed and CAMs is self-reported and is subject to the inaccuracies and omissions associated with this method of data collection.

CONCLUSION

We found survey participants used CAMs less frequently than prescription medications to treat their depressive or anxiety symptoms. Nonetheless, medical practitioners should be aware that their patients may use CAMs and seek information about such use to reduce the likelihood of adverse interactions between prescribed medication and CAMs.

摘要

背景

服用抗抑郁药或抗焦虑药的个体可能会用补充和替代医学(CAM)来替代或辅助这些药物治疗。关于社区中个体使用CAM来替代或补充他们所开的治疗焦虑和抑郁症状药物的程度,我们知之甚少。

方法

从澳大利亚堪培拉及其周边地区的7485名调查参与者的社区样本中获取有关CAM、抗抑郁药和抗焦虑药使用情况的信息。年龄在20 - 24岁、40 - 44岁或60 - 64岁的参与者还提供了社会人口学特征、身心健康方面的信息。

结果

6.29%的参与者仅使用处方药来治疗抑郁或焦虑。2.28%的参与者仅使用CAM进行治疗,另有0.59%的参与者报告同时使用这两种治疗方法。使用CAM的人和服用处方药的人心理健康问题水平相当,但使用CAM的人身体健康问题较少,神经质水平较低。然而,与既不使用CAM也不服用处方药的人相比,使用CAM的人有更多的抑郁和焦虑症状、更差的心理健康状况、更高的神经质水平和更低的掌控感。

局限性

关于处方药和CAM使用情况的信息是自我报告的,可能存在与这种数据收集方法相关的不准确和遗漏。

结论

我们发现调查参与者使用CAM治疗抑郁或焦虑症状的频率低于处方药。尽管如此,医生应该意识到他们的患者可能会使用CAM,并寻求有关这种使用情况的信息,以降低处方药和CAM之间发生不良相互作用的可能性。

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