Ho Anthony M H, Chung David C, To Edward W H, Karmakar Manoj K
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong SAR, PRC.
Can J Anaesth. 2004 Oct;51(8):838-41. doi: 10.1007/BF03018461.
To report a case of complete upper airway obstruction after topicalization with lidocaine in a completely conscious patient with partial upper airway obstruction.
A 69-yr-old man with a history of neck cancer and radiation presented for resection of recurrent neck tumour. No preoperative sedation was given. He had inspiratory and expiratory stridor but had no history of aspiration or swallowing problem. Phonation was distorted but effective. The surgeon was reluctant to perform an awake tracheostomy under local anesthesia. In preparation for a fibrescope-assisted orotracheal intubation, the non-sedated patient was given topical upper airway lidocaine during which he developed total airway obstruction and hypoxemia. He was immediately intubated with a fibrescope. His vocal cords were not edematous although the supraglottic structures appeared to be. The vocal cords were abducted and their movement was limited and not paradoxical. Tumour resection was uneventful upon successful tracheal intubation and general anesthesia. Tracheostomy at the end of the case was difficult, as expected. The patient tolerated the procedures and regained consciousness with no neurologic sequelae.
Dynamic airflow limitation associated with local anesthesia of the upper airway may lead to complete upper airway obstruction in a compromised airway. The main cause may be the loss of upper airway muscle tone, exacerbated by deep inspiration during panic.
报告一例在局部麻醉下使用利多卡因后,完全清醒且存在部分上气道梗阻的患者发生完全性上气道梗阻的病例。
一名69岁男性,有颈部癌及放疗史,因复发性颈部肿瘤切除术前来就诊。术前未给予镇静剂。他有吸气性和呼气性喘鸣,但无误吸或吞咽问题病史。发声虽有畸变但有效。外科医生不愿在局部麻醉下进行清醒气管切开术。在准备纤维支气管镜辅助经口气管插管时,未给予镇静的患者接受了上气道利多卡因局部麻醉,在此期间他出现了完全性气道梗阻和低氧血症。立即用纤维支气管镜为他插管。尽管声门上结构似乎有水肿,但他的声带没有水肿。声带外展,其活动受限且无矛盾运动。成功气管插管并实施全身麻醉后,肿瘤切除过程顺利。正如预期的那样,病例结束时气管切开术很困难。患者耐受了手术,苏醒后无神经后遗症。
与上气道局部麻醉相关的动态气流受限可能导致已受损气道发生完全性上气道梗阻。主要原因可能是上气道肌肉张力丧失,在恐慌时深呼吸会使其加剧。