Chukanov V I, Mishin V Iu, Sigaev A T, Vasil'eva I A, Osadchaia O A, Perfil'ev A V, Naumova A N, Bagdasarian T R
Probl Tuberk Bolezn Legk. 2004(8):22-4.
The efficiency of treatment was compared in 2 groups of patients with destructive pulmonary tuberculosis and isolation of multidrug resistant Mycobacteria. In 43 patients of a study group, artificial pneumothorax (AP) was used during chemotherapy with reserve drugs while 43 patients of a control group received chemotherapy alone. AP was shown to be highly effective in treating patients with destructive pulmonary tuberculosis who isolated multidrug resistant Mycobacteria. Moreover, by the end of 12-month therapy, AP in combination with chemotherapy ensured cessation of bacterial isolation in 88.7% and cavernous closure in the lung in 86.8%, which was almost twice higher than that with therapy with reserve antituberculous drugs.
对两组患有破坏性肺结核且分离出耐多药分枝杆菌的患者的治疗效果进行了比较。在研究组的43例患者中,在使用储备药物进行化疗期间采用了人工气胸(AP),而对照组的43例患者仅接受化疗。结果表明,AP在治疗分离出耐多药分枝杆菌的破坏性肺结核患者方面非常有效。此外,在12个月治疗结束时,AP联合化疗可确保88.7%的患者停止细菌分离,86.8%的患者肺部空洞闭合,这几乎是使用储备抗结核药物治疗的两倍。