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南非东开普省乌姆塔塔私人诊所抗菌药物的处方模式。

Prescribing patterns of antimicrobial agents in private practice in Umtata, Eastern Cape, South Africa.

作者信息

Katende-Kyenda Nl, Dambisya Ym, Spring G

机构信息

Department of Pharmacology, Faculty of Health Sciences, University of Transkei, UNITRA 5117, South Africa.

出版信息

Cent Afr J Med. 2004 Jan-Feb;50(1-2):7-10.

Abstract

OBJECTIVE

To describe the prescription patterns of antimicrobial drugs in the private sector in Umtata.

DESIGN

Descriptive, retrospective study.

SETTING

Umtata Pharmacy, Umtata (a town in the Eastern Cape).

MAIN OUTCOME MEASURES

Prescription patterns and quality of prescription indicators.

METHODS

Retrospective analysis of all prescriptions for antimicrobial drugs between 1 January and 31 December 2000, noting the method of payment, number of drugs, use of generic or brand name, and also whether or not the following were stated: diagnosis, dose, dosage form, dosing interval and duration of treatment.

RESULTS

There were 2352 prescriptions, of which 57.7% were paid through medical aid; 41.7% by cash, while 0.6% of the prescriptions had no form of payment stated. Only 10.4% of prescriptions used generic names exclusively; 83.2% used brand names alone and 6.4% had both generic and brand names. The form of payment apparently influenced the number of items per prescription, with the average number for medical aid prescriptions higher than for those paid for in cash (2.71 vs. 2.11; p < 0.001). Of the prescriptions 12.5% had five or more drugs. The diagnosis was not stated in 94.3% of prescriptions, the dose and duration of treatment were not properly stated in 53.3% and 59.6% of prescriptions respectively. The dosage forms and dosing intervals were stated in 99% and 85% of prescriptions, respectively. The most commonly prescribed antimicrobials were amoxycillin, metronidazole and ketoconazole.

CONCLUSION

The low rate of generic prescribing and the incomplete nature of many prescriptions are a cause for concern. Their cost implications and possible effect on the effective use of antimicrobial agents are discussed.

摘要

目的

描述乌姆塔塔私营部门抗菌药物的处方模式。

设计

描述性回顾性研究。

地点

东开普省乌姆塔塔镇的乌姆塔塔药房。

主要观察指标

处方模式和处方指标质量。

方法

对2000年1月1日至12月31日期间所有抗菌药物处方进行回顾性分析,记录支付方式、药物数量、通用名或品牌名的使用情况,以及是否注明以下内容:诊断、剂量、剂型、给药间隔和治疗持续时间。

结果

共有2352张处方,其中57.7%通过医疗救助支付;41.7%用现金支付,而0.6%的处方未注明支付形式。仅10.4%的处方仅使用通用名;83.2%仅使用品牌名,6.4%同时使用通用名和品牌名。支付形式显然影响每张处方的药品数量,医疗救助处方的平均数量高于现金支付处方(2.71对2.11;p<0.001)。12.5%的处方有五种或更多药物。94.3%的处方未注明诊断,53.3%和59.6%的处方分别未正确注明剂量和治疗持续时间。99%和85%的处方分别注明了剂型和给药间隔。最常开具的抗菌药物是阿莫西林、甲硝唑和酮康唑。

结论

通用名处方率低以及许多处方不完整令人担忧。讨论了其成本影响以及对抗菌药物有效使用的可能影响。

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