一名类风湿关节炎患者的多发性皮肤网状组织细胞瘤。
Multiple cutaneous reticulohistiocytomas in a patient with rheumatoid arthritis.
作者信息
Vieira Ricardo, Cordeiro Margarida Robalo, Mariano Angelina, Reis Jose Pedro, Tellechea Oscar, Figueiredo Americo
机构信息
Department of Dermatology, University Hospital, Coimbra, Portugal.
出版信息
Dermatol Online J. 2004 Oct 15;10(2):11.
A 64-year-old woman with a long-standing peripheral symmetric polyarthritis with positive rheumatoid serology was evaluated for multiple asymptotic papulonodules of fingers, mentum, lower lip, ears, and eyelids. Histopathologic examination showed a dermal infiltrate composed of histiocytes, multinucleate giant cells with ground-glass cytoplasm, and lymphocytes, suggestive of reticulohistiocytoma. The possibilities of multicentric reticulohistiocytosis with positive rheumatoid serology or coexistence of multiple cutaneous reticulohistiocytomas and rheumatoid arthritis are discussed.
一名64岁女性，患有长期的周围对称性多关节炎，类风湿血清学检查呈阳性，因手指、颏部、下唇、耳部及眼睑出现多个无症状丘疹结节而接受评估。组织病理学检查显示真皮浸润由组织细胞、具有毛玻璃样细胞质的多核巨细胞和淋巴细胞组成，提示为网状组织细胞瘤。讨论了类风湿血清学阳性的多中心网状组织细胞增生症或多发性皮肤网状组织细胞瘤与类风湿关节炎并存的可能性。
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