幽门螺杆菌抗体检测对成年人的年龄依赖性准确性，特别强调萎缩性胃炎。
Age-dependent accuracy of Helicobacter pylori antibody assays for adults, with special emphasis on atrophic gastritis.
作者信息
Salomaa-Räsänen A, Kosunen T U, Mattila J, Sarna S, Rautelin H
机构信息
Department of Bacteriology and Immunology, Haartman Institute, PO Box 21 (Haartmaninkatu 3), FIN-00014 University of Helsinki, Helsinki, Finland.
出版信息
Clin Diagn Lab Immunol. 2004 Nov;11(6):1185-8. doi: 10.1128/CDLI.11.6.1185-1188.2004.
Abstract
The accuracy of Helicobacter pylori antibody assays for 561 consecutive adult outpatients who had undergone gastroscopy was studied. The sensitivity of an immunoglobulin G test was 99 to 100% for all age groups, but the specificity declined by age group, from 99% for those aged 15 to 49 years to 75% for those aged > or =65 years. The exclusion of false-positive results for patients with atrophic gastritis improved the specificity to 93 to 97% for the older age groups.
摘要
对561例连续接受胃镜检查的成年门诊患者的幽门螺杆菌抗体检测准确性进行了研究。免疫球蛋白G检测对所有年龄组的敏感性为99%至100%，但特异性随年龄组下降，从15至49岁人群的99%降至≥65岁人群的75%。排除萎缩性胃炎患者的假阳性结果后，老年组的特异性提高到93%至97%。
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