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Parmodel:一个用于蛋白质自动比较建模的网络服务器。

Parmodel: a web server for automated comparative modeling of proteins.

作者信息

Uchôa Hugo Brandão, Jorge Guilherme Eberhart, Freitas Da Silveira Nelson José, Camera João Carlos, Canduri Fernanda, De Azevedo Walter Filgueira

机构信息

Departamento de Física UNESP, São José do Rio Preto, SP 15054-000, Brazil.

出版信息

Biochem Biophys Res Commun. 2004 Dec 24;325(4):1481-6. doi: 10.1016/j.bbrc.2004.10.192.

Abstract

Parmodel is a web server for automated comparative modeling and evaluation of protein structures. The aim of this tool is to help inexperienced users to perform modeling, assessment, visualization, and optimization of protein models as well as crystallographers to evaluate structures solved experimentally. It is subdivided in four modules: Parmodel Modeling, Parmodel Assessment, Parmodel Visualization, and Parmodel Optimization. The main module is the Parmodel Modeling that allows the building of several models for a same protein in a reduced time, through the distribution of modeling processes on a Beowulf cluster. Parmodel automates and integrates the main softwares used in comparative modeling as MODELLER, Whatcheck, Procheck, Raster3D, Molscript, and Gromacs. This web server is freely accessible at .

摘要

Parmodel是一个用于蛋白质结构自动比较建模和评估的网络服务器。该工具的目的是帮助缺乏经验的用户进行蛋白质模型的建模、评估、可视化和优化,同时也帮助晶体学家评估通过实验解析的结构。它分为四个模块:Parmodel建模、Parmodel评估、Parmodel可视化和Parmodel优化。主要模块是Parmodel建模,它通过在Beowulf集群上分布建模过程,能够在较短时间内为同一蛋白质构建多个模型。Parmodel自动集成了比较建模中使用的主要软件,如MODELLER、Whatcheck、Procheck、Raster3D、Molscript和Gromacs。这个网络服务器可通过[具体网址]免费访问。 (原文此处缺少具体网址)

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