Brooks M E, Rogers N, Ransome R, Leffall L D
Department of Pathology, Howard University Hospital, Washington, DC.
J Surg Oncol. 1992 Apr;49(4):239-44. doi: 10.1002/jso.2930490407.
In the period from January 1, 1976 to December 31, 1988, we reviewed the charts of 33 patients treated for carcinoma of the thyroid at Howard University Hospital. The three non-black patients (two Whites and one Pakistani) were excluded from the study. There were 19 females and 11 males. Of the 30 cases elevated, 10 were papillary, 7 were follicular variant of papillary, 8 were follicular, 3 were undifferentiated (anaplastic), and 2 were medullary. Ten patients had either distant metastasis (Hoffman, South Med J 80:741, 1987) or locally advanced disease in the neck (Woolner et al., Am J Surg 102:354, 1961.) at the time of diagnosis. The treatment of these lesions depended on, among other variables, the cell type, the extent of the lesion, and the personal preference of the attending surgeon. Carcinoma of the thyroid remains an uncommon lesion in Black patients. Because of its rarity, the diagnosis may often be delayed and, as a result, patients may first come to attention with a more advanced stage of this disease. To prevent this occurrence, a high index of suspicion must be maintained for all thyroid nodules, and appropriate diagnostic steps taken. Diagnostic and treatment options are discussed.
在1976年1月1日至1988年12月31日期间,我们查阅了霍华德大学医院接受甲状腺癌治疗的33例患者的病历。3名非黑人患者(2名白人、1名巴基斯坦人)被排除在研究之外。患者中有19名女性和11名男性。在这30例确诊病例中,乳头状癌10例,乳头状癌滤泡变体7例,滤泡状癌8例,未分化(间变性)癌3例,髓样癌2例。10例患者在诊断时已有远处转移(霍夫曼,《南方医学杂志》80:741,1987)或颈部局部晚期疾病(伍尔纳等人,《美国外科杂志》102:354,1961)。这些病变的治疗取决于多种因素,包括细胞类型、病变范围以及主刀医生的个人偏好。甲状腺癌在黑人患者中仍然是一种罕见的病变。由于其罕见性,诊断往往会延迟,结果患者可能在疾病更晚期才引起注意。为防止这种情况发生,对于所有甲状腺结节都必须保持高度怀疑,并采取适当的诊断措施。本文讨论了诊断和治疗选择。