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医院内由稳定伯克霍尔德菌引起的血流感染

Nosocomial bloodstream infections with Burkholderia stabilis.

作者信息

Otağ F, Ersöz G, Salcioğlu M, Bal C, Schneider I, Bauernfeind A

机构信息

Faculty of Medicine, Mersin University, Mersin, Tip Fakultesi, Mikrobiyoloji ve Klinik Mikrobiyoloji AD, 33079 Mersin, Turkey.

出版信息

J Hosp Infect. 2005 Jan;59(1):46-52. doi: 10.1016/j.jhin.2004.06.034.

Abstract

Burkholderia stabilis was grown from blood cultures of seven patients presenting with signs and symptoms of septicaemia in the intensive care unit at Mersin University Hospital, Mersin, Turkey between July and October 2002. Four patients had one B. stabilis-positive blood culture, two patients had two, and one patient had four. Isolates from six of seven patients had the same resistotype and random amplified polymorphic DNA analysis type. Despite treatment with ciprofloxacin and imipenem, to which the strains were susceptible, all patients died one to eight days after isolation of B. stabilis from their blood. B. stabilis should be regarded as an opportunistic pathogen that may cause nosocomial bloodstream infections.

摘要

2002年7月至10月间,在土耳其梅尔辛大学医院重症监护病房,从7例出现败血症体征和症状的患者血培养物中培养出了稳定伯克霍尔德菌。4例患者有1次血培养为稳定伯克霍尔德菌阳性,2例患者有2次,1例患者有4次。7例患者中的6例分离株具有相同的耐药型和随机扩增多态性DNA分析类型。尽管使用了环丙沙星和亚胺培南进行治疗(菌株对这两种药物敏感),但所有患者在血中分离出稳定伯克霍尔德菌后1至8天死亡。稳定伯克霍尔德菌应被视为一种可能导致医院血流感染的机会致病菌。

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