Finak G, Godin N, Hallett M, Pepin F, Rajabi Z, Srivastava V, Tang Z
McGill Centre for Bioinformatics, 3775 University Street, McGill University, Montreal, Canada H3A 2B4.
Bioinformatics. 2005 Apr 15;21(8):1745-6. doi: 10.1093/bioinformatics/bti170. Epub 2004 Nov 30.
We introduce a development platform especially tailored to Bioinformatics research and software development. BIAS (Bioinformatics Integrated Application Software) provides the tools necessary for carrying out integrative Bioinformatics research requiring multiple datasets and analysis tools. It follows an object-relational strategy for providing persistent objects, allows third-party tools to be easily incorporated within the system and supports standards and data-exchange protocols common to Bioinformatics.
BIAS is an OpenSource project and is freely available to all interested users at http://www.mcb.mcgill.ca/~bias/. This website also contains a paper containing a more detailed description of BIAS and a sample implementation of a Bayesian network approach for the simultaneous prediction of gene regulation events and of mRNA expression from combinations of gene regulation events.
我们推出了一个专门为生物信息学研究和软件开发量身定制的开发平台。BIAS(生物信息学集成应用软件)提供了开展需要多个数据集和分析工具的综合生物信息学研究所需的工具。它采用对象关系策略来提供持久对象,允许将第三方工具轻松集成到系统中,并支持生物信息学通用的标准和数据交换协议。
BIAS是一个开源项目,所有感兴趣的用户都可以从http://www.mcb.mcgill.ca/~bias/免费获取。该网站还包含一篇论文,其中对BIAS进行了更详细的描述,以及一个用于同时预测基因调控事件和从基因调控事件组合中预测mRNA表达的贝叶斯网络方法的示例实现。