Brcić Irena
Institut za medicinska istrazivanja i medicinu rada, Zagreb.
Arh Hig Rada Toksikol. 2004 Nov;55(4):291-300.
Aromatic hydrocarbons benzene, toluene, ethylbenzene, and isomeric xylenes (BTEX) are volatile organic compounds widespread in the biosphere because of their physical and chemical properties and their use. They are major constituents of gasoline, and vehicular traffic is the main source of BTEX in the environment. Significant additional exposure to BTEX results from tobacco smoking. General population is more or less permanently exposed to BTEX. This review summarises their distribution in the environment, analytical methods for BTEX determination in biological samples, and published data on BTEX concentrations in blood, exhaled air and urine samples of general population. The paper also describes toxic effects of BTEX on human health associated exclusively with professional exposure. Concentrations of these compounds in biological samples collected from general population reflect environmental pollution. Biological monitoring of people exposed to environmental BTEX concentrations is the first step toward evaluating health risk.
芳香烃苯、甲苯、乙苯和异构二甲苯(BTEX)是挥发性有机化合物,由于其物理和化学性质及其用途,它们广泛存在于生物圈中。它们是汽油的主要成分,而车辆交通是环境中BTEX的主要来源。吸烟会导致大量额外接触BTEX。普通人群或多或少会长期接触BTEX。本综述总结了它们在环境中的分布、生物样品中BTEX测定的分析方法,以及普通人群血液、呼出气体和尿液样本中BTEX浓度的已发表数据。本文还描述了BTEX对人类健康的毒性作用,这些作用仅与职业接触有关。从普通人群收集的生物样品中这些化合物的浓度反映了环境污染。对暴露于环境BTEX浓度下的人群进行生物监测是评估健康风险的第一步。