Blake Stephen M, Gie Graham A
The Princess Elizabeth Orthopaedic Centre, Royal Devon and Exeter Hospital, Exeter, Devon, England.
J Arthroplasty. 2004 Dec;19(8):1050-4. doi: 10.1016/s0883-5403(04)00350-x.
Giant cell tumors (GCTs) of bone typically present in adults between the ages of 20 and 50 with the symptoms of progressive pain and local swelling. Females are slightly more often affected than males. GCTs tend to arise in epiphyses of long tubular bones. The typical radiographic appearances are of geographical radiolucency and cortical thinning, without internal mineralization. GCTs represent 5% of all primary bone tumours. Although benign, GCTs are locally aggressive entities producing expansive and lytic lesions. We present the case of a young man with a GCT of his pelvis who could not be treated by previously described methods because of the size of the lesion, its location, and the effects it had on surrounding bony structures.
骨巨细胞瘤(GCT)通常发生于20至50岁的成年人,表现为进行性疼痛和局部肿胀症状。女性受累略多于男性。GCT倾向于发生在长管状骨的骨骺。典型的放射学表现为地图样透亮区和皮质变薄,无内部矿化。GCT占所有原发性骨肿瘤的5%。尽管GCT是良性的,但它们是具有局部侵袭性的实体,可产生膨胀性和溶骨性病变。我们报告一例骨盆骨巨细胞瘤的年轻男性病例,由于病变的大小、位置及其对周围骨结构的影响,无法采用先前描述的方法进行治疗。