Grant Peter, Nordsletten Lars
Orthopaedic Centre, Ullevål University Hospital, Kirkeveien 166, N-0407 Oslo, Norway.
J Bone Joint Surg Am. 2004 Dec;86(12):2636-41. doi: 10.2106/00004623-200412000-00008.
The Lord prosthesis has been used rather extensively for total hip arthroplasty. In 1981, we began a prospective study for the purpose of determining the long-term results associated with the use of this prosthesis. In the present report, we describe the results for the living patients after a mean duration of follow-up of 17.5 years (range, fifteen to twenty years).
One hundred and two patients (116 hips) with a mean age of sixty-two years at the time of the index arthroplasty were included in the study. Eighty-nine hips were in women, and twenty-seven were in men. The Lord femoral prosthesis (with a 32-mm head) and the Lord threaded cup were used in all patients. The protocol included radiographic analysis, recording of complications, and a clinical evaluation. The patients were evaluated at one to four years, five to nine years, and fifteen to twenty years.
One patient (one hip) refused to participate and forty-two patients (forty-five hips) died with the femoral component in place, leaving fifty-nine patients (seventy hips) available for clinical assessment. One femoral component was revised because of mechanical loosening, and one was revised because of a stem fracture. One stem appeared to be loose radiographically. Kaplan-Meier survivorship analysis with revision of the femoral component because of mechanical loosening, stem fracture, or radiographic loosening as the end point revealed a cumulative survival rate of 98% (95% confidence interval, 95.3% to 100.7%) (with twenty-eight hips at risk) at 17.5 years. Seventeen acetabular components were revised because of mechanical loosening, and sixteen were considered to be radiographically loose. Kaplan-Meier survivorship analysis with revision of the acetabular component because of mechanical or radiographic loosening as the end point revealed a cumulative survival rate of 65% (95% confidence interval, 53% to 72%) (with twenty-two hips at risk) at 17.5 years.
We believe that the survival rate of the Lord femoral component after 17.5 years of follow-up was excellent. However, there was a substantial rate of proximal femoral bone loss. The results associated with the threaded cup were rather poor, and many patients had a loose implant but few symptoms. We recommend that patients with these implants be followed closely so that revision can be performed before substantial destruction of the acetabulum has occurred.
Therapeutic study, Level II-1 (prospective cohort study). See Instructions to Authors for a complete description of levels of evidence.
洛德假体已广泛应用于全髋关节置换术。1981年,我们开展了一项前瞻性研究,以确定使用该假体的长期效果。在本报告中,我们描述了平均随访17.5年(范围为15至20年)后存活患者的结果。
本研究纳入了102例患者(116髋),初次置换时的平均年龄为62岁。其中89髋为女性,27髋为男性。所有患者均使用洛德股骨假体(头部直径32 mm)和洛德螺纹髋臼杯。研究方案包括影像学分析、并发症记录和临床评估。患者分别在1至4年、5至9年以及15至20年时接受评估。
1例患者(1髋)拒绝参与,42例患者(45髋)在股骨假体在位时死亡,剩余59例患者(70髋)可供临床评估。1例股骨假体因机械性松动而翻修,1例因柄部骨折而翻修。1例柄部在影像学上显示有松动。以因机械性松动、柄部骨折或影像学松动而翻修股骨假体作为终点的Kaplan-Meier生存分析显示,在17.5年时的累积生存率为98%(95%置信区间为95.3%至100.7%)(有28髋处于风险中)。17例髋臼假体因机械性松动而翻修,16例在影像学上被认为松动。以因机械性或影像学松动而翻修髋臼假体作为终点的Kaplan-Meier生存分析显示,在17.5年时的累积生存率为65%(95%置信区间为53%至72%)(有22髋处于风险中)。
我们认为,经过17.5年的随访,洛德股骨假体的生存率极佳。然而,股骨近端骨丢失率较高。螺纹髋臼杯的效果相当差,许多患者的植入物松动但症状较少。我们建议对植入这些假体的患者进行密切随访,以便在髋臼发生严重破坏之前进行翻修。
治疗性研究,II-1级(前瞻性队列研究)。有关证据水平的完整描述,请参阅《作者须知》。