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癌症疼痛的药物治疗

The pharmacologic management of cancer pain.

作者信息

Cherny Nathan I

机构信息

Cancer Pain and Palliative Medicine, Department of Medical Oncology, Shaare Zedek Medical Center, Jerusalem, Israel.

出版信息

Oncology (Williston Park). 2004 Oct;18(12):1499-515; discussion 1516, 1520-1, 1522, 1524.

Abstract

The management of cancer pain requires familiarity with a range of therapeutic strategies, including antineoplastic therapies, analgesic pharmacotherapy, and anesthetic, neurosurgical, psychological, and rehabilitation techniques. Successful pain management is characterized by implementation of the techniques with the most favorable therapeutic index for the prevailing circumstances, along with provision for repeated evaluations, so that a favorable balance between pain relief and adverse effects is maintained. For most patients, pain management involves the administration of specific analgesic approaches. In all cases, these analgesic treatments must be skillfully integrated with the management of other symptoms.

摘要

癌症疼痛的管理需要熟悉一系列治疗策略,包括抗肿瘤治疗、镇痛药物治疗以及麻醉、神经外科、心理和康复技术。成功的疼痛管理的特点是在当前情况下实施具有最有利治疗指数的技术,并进行反复评估,以便在疼痛缓解和不良反应之间保持良好的平衡。对于大多数患者来说,疼痛管理涉及采用特定的镇痛方法。在所有情况下,这些镇痛治疗都必须巧妙地与其他症状的管理相结合。

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