Nielsen Karen C, Guller Ulrich, Steele Susan M, Klein Stephen M, Greengrass Roy A, Pietrobon Ricardo
Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA.
Anesthesiology. 2005 Jan;102(1):181-7. doi: 10.1097/00000542-200501000-00027.
Regional anesthesia is increasing in popularity for ambulatory surgical procedures. Concomitantly, the prevalence of obesity in the United States population is increasing. The objective of the present investigation was to assess the impact of body mass index (BMI) on patient outcomes after ambulatory regional anesthesia.
This study was based on prospectively collected data including 9,038 blocks performed on 6,920 patients in a single ambulatory surgery center. Patients were categorized into three groups according to their BMI (<25 kg/m2, 25-29 kg/m2, > or =30 kg/m2). Block efficacy, rate of acute complications, postoperative pain (at rest and with movement), postoperative nausea and vomiting, rate of unscheduled hospital admissions, and overall patient satisfaction were assessed. Linear and logistic multivariable analyses were used to obtain the risk-adjusted effect of BMI on these outcomes.
Of all patients 34.8% had a BMI <25 kg/m2, 34.0% were overweight (BMI 25-29 kg/m2), and 31.3% were obese (BMI > or = 30 kg/m2). Patients with BMI > or =30 kg/m2 were 1.62 times more likely to have a failed block (P = 0.04). The unadjusted rate of acute complications was higher in obese patients (P = 0.001). However, when compared with patients with a normal BMI, postoperative pain at rest, unanticipated admissions, and overall satisfaction were similar in overweight and obese patients.
The present investigation shows that obesity is associated with higher block failure and complication rates in surgical regional anesthesia in the ambulatory setting. Nonetheless, the rate of successful blocks and overall satisfaction remained high in patients with increased BMI. Therefore, overweight and obese patients should not be excluded from regional anesthesia procedures in the ambulatory setting.
区域麻醉在门诊外科手术中的应用越来越广泛。与此同时,美国人群中的肥胖患病率也在上升。本研究的目的是评估体重指数(BMI)对门诊区域麻醉后患者预后的影响。
本研究基于前瞻性收集的数据,包括在单一门诊手术中心对6920例患者实施的9038次阻滞。根据患者的BMI将其分为三组(<25kg/m²、25 - 29kg/m²、≥30kg/m²)。评估阻滞效果、急性并发症发生率、术后疼痛(静息时和活动时)、术后恶心呕吐、非计划住院率以及患者总体满意度。采用线性和逻辑多变量分析来获得BMI对这些预后的风险调整效应。
所有患者中,34.8%的BMI<25kg/m²,34.0%为超重(BMI 25 - 29kg/m²),31.3%为肥胖(BMI≥30kg/m²)。BMI≥30kg/m²的患者阻滞失败的可能性高1.62倍(P = 0.04)。肥胖患者的急性并发症未调整发生率更高(P = 0.001)。然而,与BMI正常的患者相比,超重和肥胖患者静息时的术后疼痛、意外住院率及总体满意度相似。
本研究表明,在门诊环境下,肥胖与外科区域麻醉中更高的阻滞失败率和并发症发生率相关。尽管如此,BMI增加的患者中阻滞成功率和总体满意度仍然较高。因此,超重和肥胖患者不应被排除在门诊区域麻醉手术之外。