[The animal model of anxious depression: persistence of behavior pathology].
作者信息
Avgustinovich D F, Kovalenko I L, Kudriavtseva N N
出版信息
Ross Fiziol Zh Im I M Sechenova. 2004 Oct;90(10):1235-45.
PMID:15628180
Abstract
It has been shown that chronic psychoemotional stress caused by repeated experience of defeats in agonistic interactions during 30 days led to development of the anxiety depression--like state accompanied by pronounced anxiety, behavioral deficit, decreased communication, and increased depressiveness as estimated by various behavioral tests in male mice. This psychopathological state still existed after 1-2 weeks living with females in comfortable conditions (without confrontations with other males), that testified to persistence of behavior pathology.
摘要
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