Vranić Edina, Lacević Amela, Mehmedagić Aida, Uzunović Alija
Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Sarajevo, Bosnia and Herzegovina.
Bosn J Basic Med Sci. 2004 Oct;4(4):51-8. doi: 10.17305/bjbms.2004.3362.
In order to achieve the multi-claim products required for the dental care category, it is necessary for the formulator to use a variety of different ingredients. This places a number of demands on the development process. Innovations in the areas of pharmaceutical technology have contributed to the formulation of the products having superior efficacy as well as other attributes that may contribute to clinical response and patient acceptability. Improved clinical efficacy and tolerability, along with conditioning signals, should encourage patient compliance with oral hygiene further complementing professional efforts directed at disease prevention. The most effective way of preventing the development of dental disease is in controlling the production of dental plaque. It is formed by microbial action. The removal of plaque from the teeth and related areas is essential for the maintenance of a healthy mouth. In this paper we have presented the main components of toothpastes and mouthwashes. For the active ingredients, their supposed effect as therapeutic agents is also explained.
为了实现口腔护理品类所需的多功效产品,配方设计师有必要使用多种不同的成分。这对研发过程提出了诸多要求。制药技术领域的创新有助于开发出具有卓越功效以及其他可能有助于临床反应和患者接受度的特性的产品。提高临床疗效和耐受性,以及调节信号,应能鼓励患者进一步遵守口腔卫生要求,进一步补充针对疾病预防的专业措施。预防牙齿疾病发展的最有效方法是控制牙菌斑的产生。牙菌斑是由微生物作用形成的。从牙齿和相关区域清除牙菌斑对于保持口腔健康至关重要。在本文中,我们介绍了牙膏和漱口水的主要成分。对于活性成分,还解释了它们作为治疗剂的假定作用。