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四种常见性传播疾病之间人口统计学和地理空间风险因素的相互关系。

The interrelation of demographic and geospatial risk factors between four common sexually transmitted diseases.

作者信息

Monteiro E F, Lacey C J N, Merrick D

机构信息

Department of Genitourinary Medicine, Leeds General Infirmary, Leeds, UK.

出版信息

Sex Transm Infect. 2005 Feb;81(1):41-6. doi: 10.1136/sti.2004.009431.

Abstract

OBJECTIVES

To examine the interrelation between demographic and geospatial risk factors for gonorrhoea, chlamydia, genital warts, and genital herpes.

DESIGN

We analysed age, sex, ethnicity, socioeconomic status, and area of residence for Leeds residents aged 15-54 with Neisseria gonorrhoeae, genital Chlamydia trachomatis, first episode genital herpes, and first episode genital warts during 1994-5. The 1991 UK census provided denominator population information.

RESULTS

Regression analysis showed that young age (15-24 years), ethnicity (with a gradient of risk black >white >Asian), and residence in inner city areas of deprivation were independent risk factors for all STDs. There were highly significant correlations in the geospatial distribution of incidence rates between the four infections. However, there was variation in the degree of central urban clustering, with gonorrhoea having the most restricted, and genital warts and chlamydia the widest distribution. 31% of all disease occurred in the four inner city census wards, representing 15% of the population.

CONCLUSION

These results are in keeping with core group theory applying in a unified manner to the four most common UK sexually transmitted diseases in this urban area. Population based studies are needed to clarify whether ethnicity is associated with differing sexual behavioural or mixing patterns. Our data suggest that chlamydia screening in women <25 years of age could detect 70% of cases in the community, that such programmes should give particular emphasis to implementation in core group areas, and that they could function as unifying strategies for the control of most common STDs within urban areas.

摘要

目的

研究淋病、衣原体感染、尖锐湿疣和生殖器疱疹的人口统计学及地理空间风险因素之间的相互关系。

设计

我们分析了1994 - 1995年间利兹市15 - 54岁患有淋病奈瑟菌、沙眼衣原体、初发性生殖器疱疹和初发性尖锐湿疣的居民的年龄、性别、种族、社会经济地位及居住区域。1991年英国人口普查提供了分母人群信息。

结果

回归分析表明,年轻(15 - 24岁)、种族(风险梯度为黑人>白人>亚洲人)以及居住在贫困的市中心区域是所有性传播疾病的独立风险因素。这四种感染的发病率在地理空间分布上存在高度显著的相关性。然而,城市中心聚集程度存在差异,淋病的分布最为局限,而尖锐湿疣和衣原体感染的分布最广。所有疾病的31%发生在市中心的四个普查区,占人口的15%。

结论

这些结果与核心群体理论以统一方式应用于该城市地区英国四种最常见性传播疾病的情况相符。需要开展基于人群的研究,以明确种族是否与不同的性行为或混合模式相关。我们的数据表明,对25岁以下女性进行衣原体筛查可发现社区中70%的病例,此类项目应特别强调在核心群体区域实施,并且它们可作为控制城市地区最常见性传播疾病的统一策略。

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