Leibovitch Igal, Huilgol Shyamala C, Selva Dinesh, Lun Karyn, Richards Shawn, Paver Robert
Department of Ophthalmology, Oculoplastic and Orbital Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
J Am Acad Dermatol. 2005 Feb;52(2):295-300. doi: 10.1016/j.jaad.2004.10.868.
Microcystic adnexal carcinoma (MAC) is reported to have a high rate of recurrence with standard wide local excision.
To report a large series of patients with MAC treated with Mohs micrographic surgery (MMS).
This prospective, multi-center case series included all patients in Australia treated with MMS for MAC, who were monitored by the Skin and Cancer Foundation between 1993 and 2002.
There were 44 cases; most of them (90.9%) were located in the head and neck area. In 31.8% of cases it was a recurrent tumor. In 32.5% of cases the tumor was initially misdiagnosed as basal cell carcinoma or squamous cell carcinoma. Perineural invasion was recorded in 17.5% of cases; most of them (85.7%) were previously recurrent tumors. There was only one case of recurrence (5%) out of 20 patients who completed a 5 year follow-up period after MMS.
The low 5-year recurrence rate of MAC with MMS emphasizes the importance of margin-controlled excision.
据报道，微囊性附属器癌（MAC）采用标准的广泛局部切除术后复发率很高。
报告一大系列接受莫氏显微外科手术（MMS）治疗的MAC患者。
这项前瞻性、多中心病例系列研究纳入了1993年至2002年间在澳大利亚接受MMS治疗MAC的所有患者，这些患者由皮肤与癌症基金会进行监测。
共44例；其中大多数（90.9%）位于头颈部区域。31.8%的病例为复发性肿瘤。32.5%的病例肿瘤最初被误诊为基底细胞癌或鳞状细胞癌。17.5%的病例记录有神经周围侵犯；其中大多数（85.7%）为既往复发性肿瘤。在20例接受MMS后完成5年随访期的患者中，仅1例复发（5%）。
MAC经MMS治疗后的5年低复发率强调了切缘控制切除的重要性。
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