低强度激光疗法（LLLT）治疗手部骨关节炎（OA）的随机对照试验。
Randomized controlled trial on low level laser therapy (LLLT) in the treatment of osteoarthritis (OA) of the hand.
作者信息
Brosseau Lucie, Wells George, Marchand Serge, Gaboury Isabelle, Stokes Barbara, Morin Michelle, Casimiro Lynn, Yonge Katharine, Tugwell Peter
机构信息
School of Rehabilitation Sciences, Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.
出版信息
Lasers Surg Med. 2005 Mar;36(3):210-9. doi: 10.1002/lsm.20137.
BACKGROUND AND OBJECTIVES
Low level laser therapy (LLLT) offers promising symptomatic relief of osteoarthritic (OA) pain. We examined efficacy of active LLLT versus sham LLLT on finger joints and three superficial nerves.
STUDY DESIGN/MATERIALS AND METHODS: OA-patients randomly assigned, received three treatments per week for 6 weeks of LLLT (n = 42) or sham LLLT (n = 46).
RESULTS
Pain relief, morning stiffness, and functional status did not significantly improve for LLLT versus placebo. No significant differences were found in finger range of motion, except carpometacarpal opposition (P = 0.011), grip strength, and patient global assessment which improved for active LLLT participants (P = 0.041).
CONCLUSIONS
LLLT is no better than placebo at reducing pain, morning stiffness, or improving functional status for OA-hand patients.
背景与目的
低强度激光疗法（LLLT）有望缓解骨关节炎（OA）疼痛症状。我们研究了主动式低强度激光疗法与假激光疗法对手指关节和三条浅表神经的疗效。
研究设计/材料与方法：骨关节炎患者随机分组，每周接受三次治疗，持续6周，分别接受低强度激光疗法（n = 42）或假激光疗法（n = 46）。
结果
与安慰剂相比，低强度激光疗法在缓解疼痛、晨僵和改善功能状态方面并无显著改善。除了掌指对掌（P = 0.011）、握力和患者整体评估方面，主动式低强度激光疗法参与者有所改善（P = 0.041）外，手指活动范围未发现显著差异。
结论
对于手部骨关节炎患者，低强度激光疗法在减轻疼痛、晨僵或改善功能状态方面并不优于安慰剂。
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