接受高效抗逆转录病毒治疗4年后，1型HIV感染儿童的病毒持续抑制和免疫恢复情况。
Sustained viral suppression and immune recovery in HIV type 1-infected children after 4 years of highly active antiretroviral therapy.
作者信息
Fraaij Pieter L A, Verweel Gwenda, van Rossum Annemarie M C, van Lochem Ellen G, Schutten Martin, Weemaes Corry M R, Hartwig Nico G, Burger David M, de Groot Ronald
机构信息
Department of Pediatrics, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.
出版信息
Clin Infect Dis. 2005 Feb 15;40(4):604-8. doi: 10.1086/427696. Epub 2005 Jan 25.
We report the data from a long-term study of 31 human immunodeficiency virus type 1 (HIV-1)-infected children who were treated with highly active antiretroviral therapy. A high proportion of the children had undetectable HIV-1 RNA levels. CD4+ T cell counts recovered and remained stable. Adverse events were observed frequently but were mostly mild.
我们报告了一项针对31名接受高效抗逆转录病毒治疗的1型人类免疫缺陷病毒（HIV-1）感染儿童的长期研究数据。这些儿童中很大一部分的HIV-1 RNA水平检测不到。CD4+ T细胞计数恢复并保持稳定。不良事件经常出现，但大多较为轻微。
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