Comba Pietro, Fazzo Lucia, Berrino Franco
Istituto superiore di sanità, Dipartimento ambiente e connessa prevenzione primaria, Roma.
Epidemiol Prev. 2004 Jul-Oct;28(4-5):266-71.
Subsequently to the report by a general practitioner of an apparent cluster of soft tissue sarcomas (STS) in thepopulation resident in the neighbourhood of Mantua chemical industries, two independent epidemiological studies (an incidence study and a case-control study) confirmed the original observation and extended the findings in a wider time-span. The two studies are reviewed in the present paper in order to analyze concordant and diverging findings. In the light of the available evidence, recommendations for further studies are presented and perspectives of environmental remediation are discussed.
在一名全科医生报告曼图亚化学工业附近居民中出现明显的软组织肉瘤(STS)聚集病例后,两项独立的流行病学研究(一项发病率研究和一项病例对照研究)证实了最初的观察结果,并在更广泛的时间范围内扩展了研究结果。本文对这两项研究进行了综述,以分析一致和不同的研究结果。根据现有证据,提出了进一步研究的建议,并讨论了环境修复的前景。