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实施循证指南:慢性阻塞性肺疾病的住院管理

Implementing evidence-based guidelines:inpatient management of chronic obstructive pulmonary disease.

作者信息

Harvey P A, Murphy M C, Dornom E, Berlowitz D J, Lim W K, Jackson B

机构信息

TheNorthern Clinical Research Centre, The Northern Hospital, NorthernHealth, Melbourne, Victoria, Australia.

出版信息

Intern Med J. 2005 Mar;35(3):151-5. doi: 10.1111/j.1445-5994.2004.00754.x.

Abstract

BACKGROUND

Evidence-based guidelines exist to guide inpatient management of chronic obstructive pulmonary disease (COPD) exacerbations, but we do not know how well these recommendations are adhered to.

AIMS

The aims of this study were: (i) to examine concordance with evidence based guidelines for inpatient management of COPD and (ii)to address deficiencies in compliance with guidelines by feedback of audit results and distribution of an education package.

METHODS

Retrospective chart reviews were performed using a data collection tool based on current guidelines. Forty-nine consecutive COPD admissions were audited, and results presented to medical staff. An education package was distributed directly after the presentation. One month later,35 consecutive separations were reviewed. Concordance with recommendations supported by the highest level of evidence was calculated.

RESULTS

Data were complete for 84 cases. Concordance rates ranged from 0 to 100%. Apart from initiation of systemic steroids (80-83%)and avoidance of intravenous aminophylline (100%),concordance rates were less than 60%. The only significant improvement post-intervention was for steroid duration (10 vs 29%,95% confidence interval for difference (-36.2, -1.8)).

CONCLUSION

Recommendations for steroid initiation and avoidance of aminophylline are well adhered to. Concordance rates for other recommendations were generally less than 60%. Concordance with recommendations for steroid duration was significantly improved by our intervention. The findings suggest that to facilitate evidence-based practice, alternative interventions should be evaluated.

摘要

背景

已有基于证据的指南用于指导慢性阻塞性肺疾病(COPD)急性加重期的住院治疗管理,但我们并不清楚这些建议的遵循情况如何。

目的

本研究的目的是:(i)检查与COPD住院治疗管理的循证指南的一致性,以及(ii)通过反馈审核结果和分发教育包来解决指南依从性方面的不足。

方法

使用基于现行指南的数据收集工具进行回顾性病历审查。对49例连续的COPD住院病例进行审核,并将结果告知医务人员。在汇报后直接分发教育包。1个月后,对35例连续出院病例进行审查。计算与最高级别证据支持的建议的一致性。

结果

84例病例数据完整。一致性率在0%至100%之间。除了全身用类固醇的起始使用(80 - 83%)和避免使用静脉氨茶碱(100%)外,一致性率均低于60%。干预后唯一显著改善的是类固醇使用时长(10%对29%,差异的95%置信区间为(-36.2,-1.8))。

结论

类固醇起始使用和避免使用氨茶碱的建议得到了较好的遵循。其他建议的一致性率通常低于60%。我们的干预显著提高了类固醇使用时长建议的一致性。研究结果表明,为促进循证实践,应评估其他干预措施。

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