Ural A U, Avcu F, Sayar H, Beyan C, Kocabalkan F
Uzm. Oğc. Dr. GATA Iç Hastaliklari Bilim Dali.
Mikrobiyol Bul. 1992 Jan;26(1):70-6.
Botulism is an acute form of poisoning that results from ingestion of a toxin produced by Clostridium botulinum. Botulism toxin causes their major effect by blocking neuromuscular transmission in autonomic and motor nerve terminals. Guillain Barre Syndrome, Myasthenia Graves, Lambert Eaton Myasthenic Syndrome, acute poliomyelitis and diphtheria must be considered in the differential diagnosis. Electrodiagnostic studies have been shown to be of value in differentiating botulism from other paralytic diseases. Identification of the toxin in the patients serum is diagnostic. The treatment of botulism is mainly supportive. In this study we have discussed a patient who was treated in our clinic as a botulism from unknown source, the differential diagnosis from other paralytic diseases.
肉毒中毒是一种急性中毒形式,由摄入肉毒杆菌产生的毒素引起。肉毒杆菌毒素通过阻断自主神经和运动神经末梢的神经肌肉传递发挥主要作用。鉴别诊断时必须考虑吉兰-巴雷综合征、重症肌无力、兰伯特-伊顿肌无力综合征、急性脊髓灰质炎和白喉。电诊断研究已被证明在鉴别肉毒中毒与其他麻痹性疾病方面具有价值。在患者血清中鉴定出毒素即可确诊。肉毒中毒的治疗主要是支持性治疗。在本研究中,我们讨论了一名在我们诊所接受治疗的不明来源肉毒中毒患者,以及与其他麻痹性疾病的鉴别诊断。