Unneberg Per, Strömberg Michael, Sterky Fredrik
Department of Biotechnology, Royal Institute of Technology, AlbaNova University Center, S-106 91 Stockholm, Sweden.
Bioinformatics. 2005 May 15;21(10):2528-30. doi: 10.1093/bioinformatics/bti354. Epub 2005 Mar 3.
Forage is an application which uses two neural networks for detecting single nucleotide polymorphisms (SNPs). Potential SNP candidates are identified in multiple alignments. Each candidate is then represented by a vector of features, which is classified as SNP or monomorphic by the networks. A validated dataset of SNPs was constructed from experimentally verified SNP data and used for network training and method evalutation.
The package is available at biobase.biotech.kth.se/forage/
Forage是一个使用两个神经网络来检测单核苷酸多态性(SNP)的应用程序。在多个比对中识别潜在的SNP候选者。然后每个候选者由一个特征向量表示,该向量由网络分类为SNP或单态性。从经实验验证的SNP数据构建了一个经过验证的SNP数据集,并用于网络训练和方法评估。
该软件包可在biobase.biotech.kth.se/forage/获取